Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer

Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer

Metastasis, the leading cause of death in cancer patients, requires the invasion of tumor cells through the stroma in response to migratory cues, in part provided by the extracellular matrix (ECM). Recent advances in proteomics have led to the identification of hundreds of ECM proteins, which are mo...

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Bibliographic Details
Main Authors: Janani P. Baskaran, Anna Weldy, Justinne Guarin, Gabrielle Munoz, Polina H. Shpilker, Michael Kotlik, Nandita Subbiah, Andrew Wishart, Yifan Peng, Miles A. Miller, Lenore Cowen, Madeleine J. Oudin
Format: Article
Language:English
Published: AIP Publishing LLC 2020-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5143779

Internet

http://dx.doi.org/10.1063/1.5143779

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