Attenuation of experimental colitis in glutathione peroxidase 1 and catalase double knockout mice through enhancing regulatory T cell function.

Reactive oxygen species (ROS) have been implicated in the progression of inflammatory diseases including inflammatory bowel diseases (IBD). Meanwhile, several studies suggested the protective role of ROS in immune-mediated inflammatory diseases, and it was recently reported that dextran sodium sulfa...

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Bibliographic Details
Main Authors: Hyung-Ran Kim, Anbok Lee, Eun-Jeong Choi, Jeong-Hae Kie, Woosung Lim, Hyeon Kook Lee, Byung-In Moon, Ju-Young Seoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990669?pdf=render