A quorum sensing-independent path to stumpy development in Trypanosoma brucei.

A quorum sensing-independent path to stumpy development in Trypanosoma brucei.

For persistent infections of the mammalian host, African trypanosomes limit their population size by quorum sensing of the parasite-excreted stumpy induction factor (SIF), which induces development to the tsetse-infective stumpy stage. We found that besides this cell density-dependent mechanism, the...

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Bibliographic Details
Main Authors: Henriette Zimmermann, Ines Subota, Christopher Batram, Susanne Kramer, Christian J Janzen, Nicola G Jones, Markus Engstler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5398725?pdf=render

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