Impact of the Renin–Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives

Impact of the Renin–Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives

The effects of the renin–angiotensin system (RAS) surpass the renal and cardiovascular systems to encompass other body tissues and organs, including the brain. Angiotensin II (Ang II), the most potent mediator of RAS in the brain, contributes to vascular dementia via different mechanisms, including...

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Bibliographic Details
Main Authors:	Fatima Y. Noureddine, Raffaele Altara, Fan Fan, Andriy Yabluchanskiy, George W. Booz, Fouad A. Zouein
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	International Journal of Molecular Sciences
Subjects:	blood–brain barrier ACE1 ACE2 AT2 receptor Mas receptor Ang(1–7)
Online Access:	https://www.mdpi.com/1422-0067/21/12/4268

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