Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s

Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s

Abstract Idiopathic pulmonary fibrosis (IPF) is a complex lung disease, whose build-up scar tissue is induced by several molecules. Gastrin-releasing peptide (GRP) is released from pulmonary neuroendocrine cells, alveolar macrophages, and some nerve endings in the lung. A possible role of GRP in IPF...

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Bibliographic Details
Main Authors: Ozgecan Kayalar, Fusun Oztay, Hurrem Gul Ongen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cell Communication and Signaling
Subjects:
GRP
TGF-β signalling
Wnt signalling
Pulmonary fibrosis
MRC5 cells and A549 cells
Online Access:http://link.springer.com/article/10.1186/s12964-020-00585-y

Internet

http://link.springer.com/article/10.1186/s12964-020-00585-y

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