The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels

The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels

The P2X7 receptor (P2X7R) is a key pro-inflammatory plasma membrane receptor responsible for NLRP3 inflammasome activation and IL-1β release. Various inflammatory plasma membrane receptors (e.g., IL-1 type I receptor, TNF type I and II receptors, IL-2 receptor) are shed under different pathophysiolo...

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Bibliographic Details
Main Authors: Anna Lisa Giuliani, Merhej Berchan, Juana M. Sanz, Angelina Passaro, Stefano Pizzicotti, Valentina Vultaggio-Poma, Alba Clara Sarti, Francesco Di Virgilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
cytokines
extracellular ATP
inflammation
microvesicles
purinergic signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00793/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00793/full

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