Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Star-PAP is a non-canonical poly(A) polymerase that selects mRNA targets for polyadenylation. Yet, genome-wide direct Star-PAP targets or the mechanism of specific mRNA recognition is still vague. Here, we employ HITS-CLIP to map the cellular Star-PAP binding landscape and the mechanism of global St...

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Bibliographic Details
Main Authors: Ganesh R. Koshre, Feba Shaji, Neeraja K. Mohanan, Nimmy Mohan, Jamshaid Ali, Rakesh S. Laishram
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
3′-end processing
polyadenylation
Star-PAP
RBM10
HITS-CLIP
mRNA metabolism
Online Access:https://www.mdpi.com/1422-0067/22/18/9980

Internet

https://www.mdpi.com/1422-0067/22/18/9980

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