Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by Leishmania braziliensis

Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by Leishmania braziliensis

Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about posttranscriptional regulation during LCL. MicroRNAs (miRNA...

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Bibliographic Details
Main Authors: Sara Nunes, Icaro Bonyek Silva, Mariana Rosa Ampuero, Almério Libório Lopes de Noronha, Lígia Correia Lima de Souza, Thaizza Cavalcante Correia, Ricardo Khouri, Viviane Sampaio Boaventura, Aldina Barral, Pablo Ivan Pereira Ramos, Cláudia Brodskyn, Pablo Rafael Silveira Oliveira, Natalia Machado Tavares
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
Leishmania braziliensis
microRNA
skin
transcriptome
TREM-1
human leishmaniasis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00640/full

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