Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression[S]

Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression[S]

Cyclooxygenase-2 (COX-2), the rate-limiting enzyme in prostaglandin biosynthesis, plays a key role in inflammation and circulatory homeostasis. Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors belonging to the nuclear receptor superfamily and are involve...

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Bibliographic Details
Main Authors: Mariko Hotta, Rieko Nakata, Michiko Katsukawa, Kazuyuki Hori, Saori Takahashi, Hiroyasu Inoue
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Lipid Research
Subjects:
cyclooxygenase
peroxisome proliferator-activated receptor
thymol
essential oil
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313833

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