Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents

Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents

Abstract Background Adult mesenchymal stem cells (MSCs) play a crucial role in the maintenance of tissue homeostasis and in regenerative processes. Among the different MSC types, the gingiva-derived mesenchymal stem cells (GMSCs) have arisen as a promising tool to promote the repair of damaged tissu...

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Bibliographic Details
Main Authors: Chiara Giacomelli, Letizia Natali, Marco Nisi, Marinella De Leo, Simona Daniele, Barbara Costa, Filippo Graziani, Mario Gabriele, Alessandra Braca, M. Letizia Trincavelli, Claudia Martini
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Stem Cell Research & Therapy
Subjects:
Human gingival mesenchymal stem cells
Tumour necrosis factor-alpha
Endothelial cells
Cytokine release
Ribes nigrum
Online Access:http://link.springer.com/article/10.1186/s13287-018-0880-7

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http://link.springer.com/article/10.1186/s13287-018-0880-7

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