Diagnostic Value of Metagenomic Next-Generation Sequencing for the Detection of Pathogens in Bronchoalveolar Lavage Fluid in Ventilator-Associated Pneumonia Patients

Diagnostic Value of Metagenomic Next-Generation Sequencing for the Detection of Pathogens in Bronchoalveolar Lavage Fluid in Ventilator-Associated Pneumonia Patients

Objective: To evaluate the diagnostic performance of metagenomic next-generation sequencing (mNGS) using bronchoalveolar lavage fluid (BALF) in patients with ventilator-associated pneumonia (VAP).Methods: BALF samples of 72 patients with VAP were collected from August 2018 to May 2020. The diagnosti...

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Bibliographic Details
Main Authors: Xiaowei Fang, Qing Mei, Xiaoqin Fan, Chunyan Zhu, Tianjun Yang, Lei Zhang, Shike Geng, Aijun Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Microbiology
Subjects:
metagenomics next-generation sequencing
bronchoalveolar lavage fluid
ventilator-associated pneumonia
mixed infection
diagnostic value
intensive care unit
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.599756/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2020.599756/full

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