Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-AHCP−3 Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes

Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-AHCP−3 Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes

Abstract Background The centromere is the specialized chromatin region that directs chromosome segregation. The kinetochore assembles on the centromere, attaching chromosomes to microtubules in mitosis. The centromere position is usually maintained through cell cycles and generations. However, new c...

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Bibliographic Details
Main Authors: Jing Zhu, Kevin Chi Lok Cheng, Karen Wing Yee Yuen
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Epigenetics & Chromatin
Subjects:
De novo centromeres
Neocentromeres
Centromere establishment
Artificial chromosomes
Epigenetics
Chromatin environment
Online Access:http://link.springer.com/article/10.1186/s13072-018-0185-1

Internet

http://link.springer.com/article/10.1186/s13072-018-0185-1

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