Combination of Photodynamic Therapy and a Flagellin-Adjuvanted Cancer Vaccine Potentiated the Anti-PD-1-Mediated Melanoma Suppression

Combination of Photodynamic Therapy and a Flagellin-Adjuvanted Cancer Vaccine Potentiated the Anti-PD-1-Mediated Melanoma Suppression

Immune checkpoint inhibitors become a standard therapy for malignant melanoma. As immune checkpoint inhibitor monotherapies proved to have limited efficacy in significant portion of patients, it is envisaged that combination with other therapeutic modalities may improve clinical outcomes. We investi...

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Bibliographic Details
Main Authors: Hye Suk Hwang, Kondareddy Cherukula, Yong Jun Bang, Veena Vijayan, Myeong Ju Moon, Jayalakshmi Thiruppathi, Sao Puth, Yong Yeon Jeong, In-Kyu Park, Shee Eun Lee, Joon Haeng Rhee
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
photodynamic therapy
FlaB-adjuvanted peptide vaccine
PD-1 blockade
B16-F10 melanoma
combination therapy
Online Access:https://www.mdpi.com/2073-4409/9/11/2432

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