Optimization of a low cost and broadly sensitive genotyping assay for HIV-1 drug resistance surveillance and monitoring in resource-limited settings.

Optimization of a low cost and broadly sensitive genotyping assay for HIV-1 drug resistance surveillance and monitoring in resource-limited settings.

Commercially available HIV-1 drug resistance (HIVDR) genotyping assays are expensive and have limitations in detecting non-B subtypes and circulating recombinant forms that are co-circulating in resource-limited settings (RLS). This study aimed to optimize a low cost and broadly sensitive in-house a...

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Bibliographic Details
Main Authors: Zhiyong Zhou, Nick Wagar, Joshua R DeVos, Erin Rottinghaus, Karidia Diallo, Duc B Nguyen, Orji Bassey, Richard Ugbena, Nellie Wadonda-Kabondo, Michelle S McConnell, Isaac Zulu, Benson Chilima, John Nkengasong, Chunfu Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3223235?pdf=render

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