Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis

Abstract Background Mesenchymal stem cells (MSCs) can regulate innate and adaptive immune systems through interacting with immune cells directly and secreting multiple soluble factors. Due to their immunosuppressive properties, MSC transplantation has been applied to treat many clinical and experime...

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Bibliographic Details
Main Authors: Jingjing Qi, Xiaojun Tang, Wenchao Li, Weiwei Chen, Genhong Yao, Lingyun Sun
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Myeloid-derived suppressor cells
Experimental sialadenitis
Prostaglandin E2
Online Access:http://link.springer.com/article/10.1186/s13287-020-01837-x

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