Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production

Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production

Inflammatory maturation of M1 macrophages by proinflammatory stimuli such as toll like receptor ligands results in profound metabolic reprogramming resulting in commitment to aerobic glycolysis as evidenced by repression of mitochondrial oxidative phosphorylation (OXPHOS) and enhanced glucose utiliz...

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Bibliographic Details
Main Authors:	Walter A. Baseler, Luke C. Davies, Laura Quigley, Lisa A. Ridnour, Jonathan M. Weiss, S. Perwez Hussain, David A. Wink, Daniel W. McVicar
Format:	Article
Language:	English
Published:	Elsevier 2016-12-01
Series:	Redox Biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231716300830

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