Aqueous Extract of Dendropanax morbiferus Leaves Effectively Alleviated Neuroinflammation and Behavioral Impediments in MPTP-Induced Parkinson’s Mouse Model

Aqueous Extract of Dendropanax morbiferus Leaves Effectively Alleviated Neuroinflammation and Behavioral Impediments in MPTP-Induced Parkinson’s Mouse Model

Parkinson’s disease (PD) is a commonly reported age-related neurodegenerative disorder. Microglial-mediated neuroinflammation is one of the cardinal hallmarks of various neurodegenerative disorders, including PD progression. Inadequate therapeutic strategies and substantial adverse effects of well-e...

Full description

Bibliographic Details
Main Authors:	Shin-Young Park, Govindarajan Karthivashan, Hyun Myung Ko, Duk-Yeon Cho, Joonsoo Kim, Dae Jun Cho, Palanivel Ganesan, In Su-Kim, Dong-Kug Choi
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2018/3175214

Similar Items

Dendropanax Morbiferus and Other Species from the Genus Dendropanax: Therapeutic Potential of Its Traditional Uses, Phytochemistry, and Pharmacology
by: Rengasamy Balakrishnan, et al.
Published: (2020-10-01)

Dendropanax morbiferus leaf extract facilitates oligodendrocyte development
by: Ji-Young Kim, et al.
Published: (2019-06-01)

Endothelium-dependent and endothelium-independent vasorelaxant effects of unripe Rubus coreanus Miq. and Dendropanax morbiferus H. Lév. extracts on rat aortic rings
by: Soyi Park, et al.
Published: (2020-06-01)

The Ameliorative Effects of the Ethyl Acetate Extract of Salicornia europaea L. and Its Bioactive Candidate, Irilin B, on LPS-Induced Microglial Inflammation and MPTP-Intoxicated PD-Like Mouse Model
by: Joonsoo Kim, et al.
Published: (2019-01-01)

Comparative Studies on Behavioral, Cognitive and Biomolecular Profiling of ICR, C57BL/6 and Its Sub-Strains Suitable for Scopolamine-Induced Amnesic Models
by: Govindarajan Karthivashan, et al.
Published: (2017-08-01)

Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases
by: Md. Jakaria, et al.
Published: (2019-04-01)

Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders
by: Md. Jakaria, et al.
Published: (2018-01-01)

Ameliorative potential of desalted Salicornia europaea L. extract in multifaceted Alzheimer’s-like scopolamine-induced amnesic mice model
by: Govindarajan Karthivashan, et al.
Published: (2018-05-01)

Anti-Melanogenic Effect of Dendropanax morbiferus and Its Active Components via Protein Kinase A/Cyclic Adenosine Monophosphate-Responsive Binding Protein- and p38 Mitogen-Activated Protein Kinase-Mediated Microphthalmia−Associated Transcription Factor Downregulation
by: Jung Up Park, et al.
Published: (2020-04-01)

Polyacetylene From Dendropanax morbifera Alleviates Diet-Induced Obesity and Hepatic Steatosis by Activating AMPK Signaling Pathway
by: Myung-Ji Kang, et al.
Published: (2018-05-01)

Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer’s disease
by: Govindarajan Karthivashan, et al.
Published: (2018-01-01)

The Neuroprotective Effects of GPR4 Inhibition through the Attenuation of Caspase Mediated Apoptotic Cell Death in an MPTP Induced Mouse Model of Parkinson’s Disease
by: Md Ezazul Haque, et al.
Published: (2021-04-01)

Neurotoxic Agent-Induced Injury in Neurodegenerative Disease Model: Focus on Involvement of Glutamate Receptors
by: Md. Jakaria, et al.
Published: (2018-08-01)

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice
by: Aijuan Yan, et al.
Published: (2019-01-01)

Scoparone Inhibits LPS-Simulated Inflammatory Response by Suppressing IRF3 and ERK in BV-2 Microglial Cells
by: Duk-Yeon Cho, et al.
Published: (2016-12-01)

Development and Validation of a HPLC-UV Method for Extraction Optimization and Biological Evaluation of Hot-Water and Ethanolic Extracts of Dendropanax morbifera Leaves
by: Hyung-Jae Choi, et al.
Published: (2018-03-01)

The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson's disease.
by: Joanna Schwenkgrub, et al.
Published: (2017-01-01)

Antihyperuricemic Effect of Dendropanax morbifera Leaf Extract in Rodent Models
by: Dongho Lee, et al.
Published: (2021-01-01)

Anti-inflammatory and Antioxidant Activities of Dendropanax dentiger
by: Wei-Ning Hsu, et al.
Published: (2013)

New Chemical Constituents from the Bark of <i>Dendropanax morbifera</i> Leveille and Their Evaluation of Antioxidant Activities
by: Ill-Min Chung, et al.
Published: (2019-11-01)

Mitigating Effect of <i>Lindera obtusiloba</i> Blume Extract on Neuroinflammation in Microglial Cells and Scopolamine-Induced Amnesia in Mice
by: Song-Hee Jo, et al.
Published: (2021-05-01)

Dendropanax morbifera Léveille extract ameliorates d-galactose-induced memory deficits by decreasing inflammatory responses in the hippocampus
by: Kwon Young Lee, et al.
Published: (2017-12-01)

Protective Activity of Dendropanax Morbifera Against Cisplatin-Induced Acute Kidney Injury
by: Eun-Sun Kim, et al.
Published: (2015-01-01)

Optimization of the Extraction Conditions and Biological Evaluation of <i>Dendropanax morbifera</i> H. Lev as an Anti-Hyperuricemic Source
by: Seung-Sik Cho, et al.
Published: (2018-12-01)

<i>Dendropanax morbifera</i> Protects against Renal Fibrosis in Streptozotocin-Induced Diabetic Rats
by: Richa Sachan, et al.
Published: (2020-01-01)

Papaverine inhibits α-synuclein aggregation by modulating neuroinflammation and matrix metalloproteinase-3 expression in the subacute MPTP/P mouse model of Parkinson’s disease
by: Yea-Hyun Leem, et al.
Published: (2020-10-01)

“Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease”
by: Alfredo Rodríguez-Cruz, et al.
Published: (2020-06-01)

Development aid in South Africa : a contribution or impediment to poverty alleviation?
by: Van Zonneveld, Annette Y
Published: (2015)

Protective effect of polyacetylene from Dendropanax morbifera Leveille leaves on pulmonary inflammation induced by cigarette smoke and lipopolysaccharide
by: Jae-Won Lee, et al.
Published: (2017-05-01)

Protective Effects of <i>Dendropanax morbifera</i> against Cisplatin-Induced Nephrotoxicity without Altering Chemotherapeutic Efficacy
by: Ji Su Kim, et al.
Published: (2019-07-01)

Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models
by: Palanivel Ganesan, et al.
Published: (2019-03-01)

Treatment of Dendropanax morbifera leaves extract improves diabetic phenotype and inhibits diabetes induced retinal degeneration in db/db mice
by: Myeong-Gang Heo, et al.
Published: (2018-07-01)

MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease
by: Young Cheul Chung, et al.
Published: (2013-01-01)

An in vivo immunomodulatory and anti-inflammatory study of fermented Dendropanax morbifera Léveille leaf extract
by: Biruk Tesfaye Birhanu, et al.
Published: (2018-07-01)

Comparisons of the Anti-Inflammatory Activity of <i>Dendropanax morbifera</i> LEV Leaf Extract Contents Based on the Collection Season and Concentration of Ethanol as an Extraction Solvent
by: Kyeong Jin Kim, et al.
Published: (2020-12-01)

Phytochemical Analysis, Anti-inflammatory, and Antioxidant Activities of Dendropanax dentiger Roots
by: Li Yang, et al.
Published: (2020-01-01)

NF-κB signaling contributes to the inhibitory effects of Bombyx batryticatus on neuroinflammation caused by MPTP toxicity
by: Hye-Sun Lim, et al.
Published: (2021-08-01)

Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP
by: Patrick Oeckl, et al.
Published: (2012-12-01)

Cx43 Mediates Resistance against MPP+-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells via Modulating the Mitochondrial Apoptosis Pathway
by: In-Su Kim, et al.
Published: (2016-11-01)

Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson’s Disease
by: Mustafa T. Ardah, et al.
Published: (2020-11-01)