Role of IL-4 in an experimental model of encephalitis induced by intracranial inoculation of herpes simplex virus-1 (HSV-1)

Role of IL-4 in an experimental model of encephalitis induced by intracranial inoculation of herpes simplex virus-1 (HSV-1)

Herpes simplex virus-1 (HSV-1) is a pathogen that may cause severe encephalitis in humans. In this study, we aimed to investigate the role of interleukin-4 (IL-4) in a model of HSV-1 brain infection. IL-4 knockout (IL-4-/-) and wild type (WT) C57BL/6 mice were inoculated with 10(4) plaque-forming un...

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Bibliographic Details
Main Authors: Márcia Carvalho Vilela, Roberta Dayrell de Lima Campos, Daniel Santos Mansur, David Henrique Rodrigues, Norinne Lacerda Queiroz, Graciela Kunrath Lima, Milene Alvarenga Rachid, Erna Geessien Kroon, Marco Antônio Campos, Antônio Lúcio Teixeira
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2011-04-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
vírus herpes simplex tipo 1
IL-4
neuroinflamação
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000200019&lng=en&tlng=en

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