Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model

Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model

<p>Abstract</p> <p>Background</p> <p>The effects of Hepatitis B virus (HBV) rtA181T/sW172* mutation on viral replication and pathogenicity was concerned recently. This study aimed to investigate the biological characteristics of rtA181T/sW172* mutant strain of HBV in an...

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Bibliographic Details
Main Authors: Dai Jie, Chen En-Qiang, Bai Lang, Gong Dao-Yin, Zhou Qiao-Ling, Cheng Xing, Huang Fei-Jun, Tang Hong
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Virology Journal
Subjects:
Hepatitis B virus
rtA181T/sW172* mutation
Transcription and replication
Hepatitis B surface antigen
Secretion defect
Drug sensitivity
Online Access:http://www.virologyj.com/content/9/1/280

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