The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part II: The Treg role in skin diseases pathogenesis

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part II: The Treg role in skin diseases pathogenesis

Regulatory FOXP3+ T cells (Tregs) constitute 5% to 10% of T cells in the normal human skin. They play an important role in the induction and maintenance of immunological tolerance. The suppressive effects of these cells are exerted by various mechanisms including the direct cytotoxic effect, anti-in...

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Main Authors: Bogusław Nedoszytko, Magdalena Lange, Małgorzata Sokołowska-Wojdyło, Joanna Renke, Piotr Trzonkowski, Michał Sobjanek, Aneta Szczerkowska-Dobosz, Marek Niedoszytko, Aleksandra Górska, Jan Romantowski, Justyna Czarny, Jarosław Skokowski, Leszek Kalinowski, Roman Nowicki
Format: Article
Language:English
Published: Termedia Publishing House 2017-10-01
Series:Advances in Dermatology and Allergology
Subjects:
Treg dysfunction
selected skin diseases
Online Access:https://www.termedia.pl/The-role-of-regulatory-T-cells-and-genes-involved-in-their-differentiation-in-pathogenesis-of-selected-inflammatory-and-neoplastic-skin-diseases-Part-II-The-Treg-role-in-skin-diseases-pathogenesis,7,30898,1,1.html

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