Photoactivable sphingosine as a tool to study membrane microenvironments in cultured cells[S]

Photoactivable sphingosine as a tool to study membrane microenvironments in cultured cells[S]

Human fibroblasts from normal subjects and Niemann-Pick A (NPA) disease patients were fed with two labeled metabolic precursors of sphingomyelin (SM), [3H]choline and photoactivable sphingosine, that entered into the biosynthetic pathway allowing the synthesis of radioactive phosphatidylcholine and...

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Bibliographic Details
Main Authors: Massimo Aureli, Simona Prioni, Laura Mauri, Nicoletta Loberto, Riccardo Casellato, Maria Grazia Ciampa, Vanna Chigorno, Alessandro Prinetti, Sandro Sonnino
Format: Article
Language:English
Published: Elsevier 2010-04-01
Series:Journal of Lipid Research
Subjects:
gangliosides
lipid rafts
membranes
Niemann-Pick disease
sphingolipids
sphingomyelin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520304892

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520304892

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