Glatiramer acetate increases phagocytic activity of human monocytes in vitro and in multiple sclerosis patients.

Glatiramer acetate increases phagocytic activity of human monocytes in vitro and in multiple sclerosis patients.

Beside its effects on T cells, a direct influence on cells of the myelo-monocytic lineage by GA becomes evident. Recently, we demonstrated that GA drives microglia to adopt properties of type II antigen presenting cells (APC) and increases their phagocytic activity. In the present work, we focused o...

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Bibliographic Details
Main Authors: Refik Pul, Franco Morbiducci, Jelena Škuljec, Thomas Skripuletz, Vikramjeet Singh, Ute Diederichs, Niklas Garde, Elke Verena Voss, Corinna Trebst, Martin Stangel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527448?pdf=render

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