A systemic evaluation of cardiac differentiation from mRNA reprogrammed human induced pluripotent stem cells.

Genetically unmodified cardiomyocytes mandated for cardiac regenerative therapy is conceivable by "foot-print free" reprogramming of somatic cells to induced pluripotent stem cells (iPSC). In this study, we report generation of foot-print free hiPSC through messenger RNA (mRNA) based repro...

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Bibliographic Details
Main Authors: Ashish Mehta, Vinod Verma, Manasi Nandihalli, Chrishan J A Ramachandra, Glen L Sequiera, Yuliansa Sudibyo, Yingying Chung, William Sun, Winston Shim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4113436?pdf=render