Role of Aberrant Alternative Splicing in Cancer

Alternative splicing can alter genome sequence and as a consequence, many genes change to oncogenes. This event can also affect protein function and diversity. The growing number of study elucidate the pathological influence of impaired alternative splicing events on numerous disease including cance...

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Main Authors: Milad Khorasani, Maryam Alaie, Maryam Shojaee
Format: Article
Language:English
Published: Golestan University of Medical Sciences 2021-06-01
Series:Jorjani Biomedicine Journal
Subjects:
Online Access:http://goums.ac.ir/jorjanijournal/article-1-753-en.html
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spelling doaj-cdd518bd549b4d0abee1888bb53c8f242021-10-02T04:34:26ZengGolestan University of Medical Sciences Jorjani Biomedicine Journal2645-35092021-06-019214Role of Aberrant Alternative Splicing in CancerMilad Khorasani0Maryam Alaie1Maryam Shojaee2 Department of Biochemistry and nutrition, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran Department of Clinical Biochemistry, Tarbiat Modares University, Tehran, Iran Department of Biology, Payame Noor University of Mashhad, Iran Alternative splicing can alter genome sequence and as a consequence, many genes change to oncogenes. This event can also affect protein function and diversity. The growing number of study elucidate the pathological influence of impaired alternative splicing events on numerous disease including cancer. Here, we would like to highlight the significant role of alternative splicing in cancer biology and emphasize the necessity for conducting more research into target alternative splicing as a treatment for cancer.http://goums.ac.ir/jorjanijournal/article-1-753-en.htmlcanceralternative splicing
collection DOAJ
language English
format Article
sources DOAJ
author Milad Khorasani
Maryam Alaie
Maryam Shojaee
spellingShingle Milad Khorasani
Maryam Alaie
Maryam Shojaee
Role of Aberrant Alternative Splicing in Cancer
Jorjani Biomedicine Journal
cancer
alternative splicing
author_facet Milad Khorasani
Maryam Alaie
Maryam Shojaee
author_sort Milad Khorasani
title Role of Aberrant Alternative Splicing in Cancer
title_short Role of Aberrant Alternative Splicing in Cancer
title_full Role of Aberrant Alternative Splicing in Cancer
title_fullStr Role of Aberrant Alternative Splicing in Cancer
title_full_unstemmed Role of Aberrant Alternative Splicing in Cancer
title_sort role of aberrant alternative splicing in cancer
publisher Golestan University of Medical Sciences
series Jorjani Biomedicine Journal
issn 2645-3509
publishDate 2021-06-01
description Alternative splicing can alter genome sequence and as a consequence, many genes change to oncogenes. This event can also affect protein function and diversity. The growing number of study elucidate the pathological influence of impaired alternative splicing events on numerous disease including cancer. Here, we would like to highlight the significant role of alternative splicing in cancer biology and emphasize the necessity for conducting more research into target alternative splicing as a treatment for cancer.
topic cancer
alternative splicing
url http://goums.ac.ir/jorjanijournal/article-1-753-en.html
work_keys_str_mv AT miladkhorasani roleofaberrantalternativesplicingincancer
AT maryamalaie roleofaberrantalternativesplicingincancer
AT maryamshojaee roleofaberrantalternativesplicingincancer
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