| Summary: | The microbial ecology of different indoor environments determines the human microbiome. Hence, cleaning and disinfection of indoor environments like hospitals, apartments, automobiles, etc. are of great importance. Nonaqueous surface cleaning preparations (SCPs) are often used for this purpose. A cleaning composition may contain the following compounds: primary surfactant, cosurfactant, solvent, cosolvent, organotropic (organic solubilizing) agent, hydrotropic (water solubilising) agent, water and salts, and special additives. In this paper, the efficacy of complex preparations is discussed, focusing on the chemical composition and testing methods. Particular attention is paid to quaternary ammonium compounds, i.e. surfactants with disinfection properties, which are known to act as antistatic agents, detergents, oil-in-water emulsifiers, corrosion inhibitors, and lubricants. Specificity of target microorganisms, physicochemical properties of surrounding media and treatment mode are the main factors affecting the efficacy of disinfection. Due to the enormous economic importance and massive worldwide use of surfactants and disinfectants, their environmental impact needs to be evaluated and controlled. Increased knowledge and better understanding of the antimicrobial capacity of disinfectants are essential to optimise sanitation procedures, to reduce costs, environment waste and to improve shelf life.
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