Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity

Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity

 The present study is a continuation of the scientific research works for the synthesis of anthraquinonе-containing derivatives with cyclic ring systems by the interaction of 1,2,4-trihydroxyanthraquinone (purpurin) with cyclic carboxylic acid chlorides. Series of purpurin esters containing a satur...

Full description

Bibliographic Details
Main Authors: Т. V. Kharlamova, R. B. Seidakhmetova, K. D. Praliyev
Format: Article
Language:English
Published: al-Farabi Kazakh National University 2020-03-01
Series:Eurasian Chemico-Technological Journal 
Subjects:
purpurin
acid chlorides of saturated
cyclic carboxylic acids
antimicrobial activity
Online Access:http://ect-journal.kz/index.php/ectj/article/view/929
id doaj-cdc9ec970e9642838df20186235b08f3
record_format Article
spelling doaj-cdc9ec970e9642838df20186235b08f32020-11-25T03:16:26Zengal-Farabi Kazakh National UniversityEurasian Chemico-Technological Journal 1562-39202522-48672020-03-0122110.18321/ectj929Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial ActivityТ. V. Kharlamova0R. B. Seidakhmetova1K. D. Praliyev2JSC “Institute of Chemical Sciences named after A.B. Becturov”, 106 Ualikhanov str., 050010, Almaty, KazakhstanJSC “Institute of Chemical Sciences named after A.B. Becturov”, 106 Ualikhanov str., 050010, Almaty, KazakhstanJSC “Institute of Chemical Sciences named after A.B. Becturov”, 106 Ualikhanov str., 050010, Almaty, Kazakhstan  The present study is a continuation of the scientific research works for the synthesis of anthraquinonе-containing derivatives with cyclic ring systems by the interaction of 1,2,4-trihydroxyanthraquinone (purpurin) with cyclic carboxylic acid chlorides. Series of purpurin esters containing a saturated cyclic fragment was studied for antibacterial activity about museum strains of microorganisms. The effects of these preparations in vitro about Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa АТСС 27853 and fungus Сandida albicans АТСС 10231 were studied. It has been found that the compounds with the cyclohexane fragment have possess an antimicrobial activity with strains of microorganisms Staphylococcus aureus АТСС 6538 for which the MIC value was 31.25 μg/ml. http://ect-journal.kz/index.php/ectj/article/view/929purpurinacid chlorides of saturatedcyclic carboxylic acidsantimicrobial activity
collection DOAJ
language English
format Article
sources DOAJ
author Т. V. Kharlamova
R. B. Seidakhmetova
K. D. Praliyev
spellingShingle Т. V. Kharlamova
R. B. Seidakhmetova
K. D. Praliyev
Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
Eurasian Chemico-Technological Journal 
purpurin
acid chlorides of saturated
cyclic carboxylic acids
antimicrobial activity
author_facet Т. V. Kharlamova
R. B. Seidakhmetova
K. D. Praliyev
author_sort Т. V. Kharlamova
title Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
title_short Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
title_full Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
title_fullStr Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
title_full_unstemmed Purpurin Esters Containing a Saturated Cyclic Fragment with Antimicrobial Activity
title_sort purpurin esters containing a saturated cyclic fragment with antimicrobial activity
publisher al-Farabi Kazakh National University
series Eurasian Chemico-Technological Journal 
issn 1562-3920
2522-4867
publishDate 2020-03-01
description  The present study is a continuation of the scientific research works for the synthesis of anthraquinonе-containing derivatives with cyclic ring systems by the interaction of 1,2,4-trihydroxyanthraquinone (purpurin) with cyclic carboxylic acid chlorides. Series of purpurin esters containing a saturated cyclic fragment was studied for antibacterial activity about museum strains of microorganisms. The effects of these preparations in vitro about Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa АТСС 27853 and fungus Сandida albicans АТСС 10231 were studied. It has been found that the compounds with the cyclohexane fragment have possess an antimicrobial activity with strains of microorganisms Staphylococcus aureus АТСС 6538 for which the MIC value was 31.25 μg/ml.
topic purpurin
acid chlorides of saturated
cyclic carboxylic acids
antimicrobial activity
url http://ect-journal.kz/index.php/ectj/article/view/929
work_keys_str_mv AT tvkharlamova purpurinesterscontainingasaturatedcyclicfragmentwithantimicrobialactivity
AT rbseidakhmetova purpurinesterscontainingasaturatedcyclicfragmentwithantimicrobialactivity
AT kdpraliyev purpurinesterscontainingasaturatedcyclicfragmentwithantimicrobialactivity
_version_ 1724636141704970240

Similar Items