Regulatory T Cells Induce Metastasis by Activating Tgf-Β and Enhancing the Epithelial–Mesenchymal Transition

Regulatory T Cells Induce Metastasis by Activating Tgf-Β and Enhancing the Epithelial–Mesenchymal Transition

Malignant melanoma is the most aggressive form of skin cancer; a substantial percentage of patients present with distant metastases. However, the mechanism of metastasis is not well understood. Here, we demonstrate that the administration of exogenous regulatory T cells (Tregs) into melanoma tumor-b...

Full description

Bibliographic Details
Main Authors: Eonju Oh, JinWoo Hong, Chae-Ok Yun
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
melanoma
cancer metastasis
epithelial–mesenchymal transition
tgf-β
regulatory t cells
Online Access:https://www.mdpi.com/2073-4409/8/11/1387

Similar Items

Similar Items