Deciphering the dual role and prognostic potential of PINK1 across cancer types

Deciphering the dual role and prognostic potential of PINK1 across cancer types

Metabolic rewiring and deregulation of the cell cycle are hallmarks shared by many cancers. Concerted mutations in key tumor suppressor genes, such as PTEN, and oncogenes predispose cancer cells for marked utilization of resources to fuel accelerated cell proliferation and chemotherapeutic resistanc...

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Bibliographic Details
Main Authors: Katherine Dai, Daniel P Radin, Donna Leonardi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
apoptosis; cancer; cell cycle; inflammation; metabolic stress; mitochondral quality control; mitophagy; pink1; tumor; warburg effect
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=4;spage=659;epage=665;aulast=Dai

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