Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function
Insulin resistance promotes vascular endothelial dysfunction and subsequent development of cardiovascular disease. Previously we found that skeletal muscle arteriolar flow-induced dilation (FID) was reduced following a hyperinsulinemic clamp in healthy adults. Therefore, we hypothesized that hyperin...
Main Authors: | Abeer M. Mahmoud, Mohamed M. Ali, Edwin R. Miranda, Jacob T. Mey, Brian K. Blackburn, Jacob M. Haus, Shane A. Phillips |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231717302148 |
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