Re-definition of claudin-low as a breast cancer phenotype

Re-definition of claudin-low as a breast cancer phenotype

In breast cancer, the claudin-low breast cancer subtype is remarkably diverse. Here, the authors propose that claudin-low is not a classical intrinsic breast cancer subtype, but rather a complex additional phenotype that can occur across intrinsic subtypes.

Bibliographic Details
Main Authors: Christian Fougner, Helga Bergholtz, Jens Henrik Norum, Therese Sørlie
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15574-5
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spelling doaj-cda6d23debbe4bd5b9bd7b754c0eb7c22021-05-11T08:30:46ZengNature Publishing GroupNature Communications2041-17232020-04-0111111110.1038/s41467-020-15574-5Re-definition of claudin-low as a breast cancer phenotypeChristian Fougner0Helga Bergholtz1Jens Henrik Norum2Therese Sørlie3Department of Cancer Genetics, Oslo University HospitalDepartment of Cancer Genetics, Oslo University HospitalDepartment of Cancer Genetics, Oslo University HospitalDepartment of Cancer Genetics, Oslo University HospitalIn breast cancer, the claudin-low breast cancer subtype is remarkably diverse. Here, the authors propose that claudin-low is not a classical intrinsic breast cancer subtype, but rather a complex additional phenotype that can occur across intrinsic subtypes.https://doi.org/10.1038/s41467-020-15574-5
collection DOAJ
language English
format Article
sources DOAJ
author Christian Fougner
Helga Bergholtz
Jens Henrik Norum
Therese Sørlie
spellingShingle Christian Fougner
Helga Bergholtz
Jens Henrik Norum
Therese Sørlie
Re-definition of claudin-low as a breast cancer phenotype
Nature Communications
author_facet Christian Fougner
Helga Bergholtz
Jens Henrik Norum
Therese Sørlie
author_sort Christian Fougner
title Re-definition of claudin-low as a breast cancer phenotype
title_short Re-definition of claudin-low as a breast cancer phenotype
title_full Re-definition of claudin-low as a breast cancer phenotype
title_fullStr Re-definition of claudin-low as a breast cancer phenotype
title_full_unstemmed Re-definition of claudin-low as a breast cancer phenotype
title_sort re-definition of claudin-low as a breast cancer phenotype
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-04-01
description In breast cancer, the claudin-low breast cancer subtype is remarkably diverse. Here, the authors propose that claudin-low is not a classical intrinsic breast cancer subtype, but rather a complex additional phenotype that can occur across intrinsic subtypes.
url https://doi.org/10.1038/s41467-020-15574-5
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AT jenshenriknorum redefinitionofclaudinlowasabreastcancerphenotype
AT theresesørlie redefinitionofclaudinlowasabreastcancerphenotype
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