Determination of Non-Transferrin Bound Iron, Transferrin Bound Iron, Drug Bound Iron and Total Iron in Serum in a Rats after IV Administration of Sodium Ferric Gluconate Complex by Simple Ultrafiltration Inductively Coupled Plasma Mass Spectrometric Detection

Determination of Non-Transferrin Bound Iron, Transferrin Bound Iron, Drug Bound Iron and Total Iron in Serum in a Rats after IV Administration of Sodium Ferric Gluconate Complex by Simple Ultrafiltration Inductively Coupled Plasma Mass Spectrometric Detection

A rapid, sensitive and specific ultrafiltration inductively-coupled plasma mass spectrometry method was developed and validated for the quantification of non-transferrin bound iron (NTBI), transferrin bound iron (TBI), drug bound iron (DI) and total iron (TI) in the same rat serum sample after intra...

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Bibliographic Details
Main Authors: Murali K. Matta, Christopher R. Beekman, Adarsh Gandhi, Suresh Narayanasamy, Christopher D. Thomas, Adil Mohammad, Sharron Stewart, Lin Xu, Ashok Chockalingam, Katherine Shea, Vikram Patel, Rodney Rouse
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Nanomaterials
Subjects:
inductively coupled plasma-mass spectrometry
ultrafiltration
pharmacokinetics
iron
iron gluconate
nanoparticles
Online Access:http://www.mdpi.com/2079-4991/8/2/101

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