Flexible designs of clinical trials – a graphical representation in form of a chance tree
Background: Flexible design of clinical trials may allow tailoring ongoing investigations to better suit actual circumstances such as an unexpectedly low effect size without compromising error control properties. Available statistical methods are, however, complex. Method: A two-stage flexible desig...
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| Format: | Article |
| Language: | deu |
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German Medical Science GMS Publishing House
2010-03-01
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| Series: | GMS Medizinische Informatik, Biometrie und Epidemiologie |
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| Online Access: | http://www.egms.de/static/en/journals/mibe/2010-6/mibe000102.shtml |