Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy.

Dengue virus (DENV) is the most common mosquito-borne flavivirus; it can either cause mild dengue fever or the more severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). One of the characteristic features of DHF/DSS is vascular leakage; although DENV nonstructural protein 1 (NS1) ha...

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Bibliographic Details
Main Authors: Hong-Ru Chen, Yung-Chun Chuang, Yee-Shin Lin, Hsiao-Sheng Liu, Ching-Chuan Liu, Guey-Chuen Perng, Trai-Ming Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4943727?pdf=render

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