Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy.
Dengue virus (DENV) is the most common mosquito-borne flavivirus; it can either cause mild dengue fever or the more severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). One of the characteristic features of DHF/DSS is vascular leakage; although DENV nonstructural protein 1 (NS1) ha...
Main Authors: | Hong-Ru Chen, Yung-Chun Chuang, Yee-Shin Lin, Hsiao-Sheng Liu, Ching-Chuan Liu, Guey-Chuen Perng, Trai-Ming Yeh |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-07-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4943727?pdf=render |
Similar Items
-
Macrophage migration inhibitory factor induces vascular leakage via autophagy
by: Hong-Ru Chen, et al.
Published: (2015-01-01) -
Study on the mechanisms of dengue virus nonstructural protein 1-induced vascular leakage
by: Hong-RuChen, et al.
Published: (2017) -
Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection
by: Yung-Chun Chuang, et al.
Published: (2015-01-01) -
Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability.
by: Hong-Ru Chen, et al.
Published: (2018-04-01) -
Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage.
by: Chiao-Hsuan Chao, et al.
Published: (2019-04-01)