Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation

Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation

Helper Innate lymphoid cells (ILCs) are tissue resident lymphocytes that play a critical role in a number of biological processes. Several transcription factors are required for the differentiation of hematopoietic stem cells (HSCs) into ILCs. Recent studies demonstrate GATA3 as a transcriptional re...

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Bibliographic Details
Main Authors: Dejene M. Tufa, Ashley M. Yingst, Tyler Shank, Seonhui Shim, George Devon Trahan, Jessica Lake, Renee Woods, Kenneth L. Jones, Michael R. Verneris
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
GATA3
HSCs
helper ILCs
differentiation
electroporation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00510/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00510/full

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