Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Is It Contributing to Higher Risk of Cognitive Decline and Coronary Heart Disease?

Apolipoprotein E (ApoE) is a protein playing a pivotal role in lipid homeostasis since it regulates cholesterol, triglyceride and phospholipid metabolism in the blood and the brain. APOE gene regulates the expression of this protein and has three different alleles: ε2, ε3 and ε4. Carrying an APOE4 a...

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Bibliographic Details
Main Authors: Raphaël Chouinard-Watkins, Mélanie Plourde
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/6/10/4452