Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals

Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.

Bibliographic Details
Main Authors: Aleksey Yevtodiyenko, Arkadiy Bazhin, Pavlo Khodakivskyi, Aurelien Godinat, Ghyslain Budin, Tamara Maric, Giorgio Pietramaggiori, Sandra S. Scherer, Marina Kunchulia, George Eppeldauer, Sergey V. Polyakov, Kevin P. Francis, Jeffrey N. Bryan, Elena A. Goun
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22892-9