Reduction of Oxidative Stress Attenuates Lipoapoptosis Exacerbated by Hypoxia in Human Hepatocytes

Reduction of Oxidative Stress Attenuates Lipoapoptosis Exacerbated by Hypoxia in Human Hepatocytes

Chronic intermittent hypoxia, a characteristic of obstructive sleep apnea (OSA), is associated with the progression of simple hepatic steatosis to necroinflammatory hepatitis. We determined whether inhibition of a hypoxia-induced signaling pathway could attenuate hypoxia-exacerbated lipoapoptosis in...

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Bibliographic Details
Main Authors:	Sang Youn Hwang, Su Jong Yu, Jeong-Hoon Lee, Hwi Young Kim, Yoon Jun Kim
Format:	Article
Language:	English
Published:	MDPI AG 2015-02-01
Series:	International Journal of Molecular Sciences
Subjects:	obstructive sleep apnea nonalcoholic steatohepatitis lipoapoptosis hypoxia endoplasmic reticulum stress oxidative stress
Online Access:	http://www.mdpi.com/1422-0067/16/2/3323

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