Association of Base Excision Repair Gene Polymorphisms with ESRD Risk in a Chinese Population

Association of Base Excision Repair Gene Polymorphisms with ESRD Risk in a Chinese Population

The base excision repair (BER) pathway, containing OGG1, MTH1 and MUTYH, is a major protector from oxidative DNA damage in humans, while 8-oxoguanine (8-OHdG), an index of DNA oxidation, is increased in maintenance hemodialysis (HD) patients. Four polymorphisms of BER genes, OGG1 c.977C > G (rs10...

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Bibliographic Details
Main Authors:	Zhenming Cai, Huimei Chen, Jing Tao, Wenwen Guo, Xiufang Liu, Bixia Zheng, Wei Sun, Yaping Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2012/928421

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