It takes two to tango: Ubiquitin and SUMO in the DNA damage response

The complexity of living cells is primarily determined by the genetic information encoded in DNA and gets fully disclosed upon translation. A major determinant of complexity is the reversible post-translational modification (PTM) of proteins, which generates variants displaying distinct biological p...

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Bibliographic Details
Main Authors: Serena eBologna, Stefano eFerrari
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00106/full