Incidence of anti-toxoplasma antibodies in women with high-risk pregnancy and habitual abortions

• Main Authors: Maria de la Luz Galvan Ramirez, Juan Luis Soto Mancilla, Oscar Velasco Castrejon, Roberto Perez Medina
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1995-12-01
• Series: Revista da Sociedade Brasileira de Medicina Tropical
• Subjects: Toxoplasmosis; Embarazo de alto riesgo; Aborto habitual; High-risk pregnancy; Habitual abortion
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400005
• ISSN: 0037-8682; 1678-9849

Toxoplasmosis is a zoonosis caused by Toxoplasma gondii, an obligate intracellular parasite. In pregnant women on the worldwide scale, there are seroprevalences from 7% to 51.3% and in women with abnormal pregnancies and abortions the seroprevalences vary from 17.5% to 52.3%. In Mexico, seropositivity has been found to vary from 18.2% to 44.8% in women with abnormal deliveries or abortions. This study's aim was to determine the incidence oflgG and IgM anti-Toxoplasma antibodies in women at the Gineco-Obstetrics Hospital of the Western Medical Center of the Mexican Social Security Institute. Three hundred and fifty women with high-risk pregnancies were studied, and 122 (34.9%) were found to be IgG seropositive and 76 (20.7%) were IgM positive. In one group of women with habitual abortions there were 48 (44.9%) with the preseiwe of IgG antibodies and 33 (33-3%) were IgM seropositive. Seropositivity was analyzed according to age, occupation, socio-economic level, eating raw or poorly cooked meat, and living with cats.<br>La toxoplasmosis es una zoonosis causada por Toxoplasma gondii , parãsito intracellular obligado, en mujeres embarazadas a nivel mundial existen seroprevalencias del 7% al 51.3% y mujeres con embarazos anormales y aborto varian desde 17.5% al 52.3%. En México se ha referido seropositividad del 18.2% al 44.8% en mujeres con partos anormales 6 abortos. El propósito de este trabajo consistió en determinar la frecuencia de anticuerpos antitoxoplasma IgG e IgM en mujeres del Hospital de Gineco Obstetrícia del Centro Médico de Occidente del Instituto Mexicano del Seguro Social. Se estudiaron 350 mujeres con embarazo de alto riesgo encontrando 122 (34.9%) seropositivas a IgG y 76 (20.7%) a IgM, y en un grupo de 105 mujeres con aborto habitual resultando 48 (44.9%) con presencia de anticuerpos IgG y 33 (33-3%) a IgM. Se analizó la seropositividad con la edad, ocupación, nivel socioeconómicoa, ingesta de came cruda 6 mal cocida y conviveticia can gatos.