Claudin Family Participates in the Pathogenesis of Inflammatory Bowel Diseases and Colitis-Associated Colorectal Cancer

Claudin Family Participates in the Pathogenesis of Inflammatory Bowel Diseases and Colitis-Associated Colorectal Cancer

Claudins are a multigene transmembrane protein family comprising at least 27 members. In gastrointestinal tract, claudins are mainly located in the intestinal epithelia; many types of claudins form a network of strands in tight junction plaques within the intercellular space of neighboring epithelia...

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Bibliographic Details
Main Authors: Liguo Zhu, Jing Han, Li Li, Ying Wang, Ying Li, Shenghong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel diseases
claudin
intestinal permeability
colitis-associated colorectal cancer
protein family
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01441/full

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