Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome
Abstract Background Fascin-1, a prominent actin-bundling protein, is found to be upregulated in several human carcinomas. While it is accepted that Fascin-1 expression correlates with poor clinical outcome and decreased survival in various carcinomas, its role in sarcoma such as osteosarcoma (OS) re...
Main Authors: | Matthias J. Arlt, Aleksandar Kuzmanov, Jess G. Snedeker, Bruno Fuchs, Unai Silvan, Adam A. Sabile |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-5303-3 |
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