Knockdown of Thymidine Kinase 1 Suppresses Cell Proliferation, Invasion, Migration, and Epithelial–Mesenchymal Transition in Thyroid Carcinoma Cells

Knockdown of Thymidine Kinase 1 Suppresses Cell Proliferation, Invasion, Migration, and Epithelial–Mesenchymal Transition in Thyroid Carcinoma Cells

Patients with advanced thyroid carcinoma have poor prognosis with low overall survival. Unfortunately, the underlying mechanisms of thyroid carcinoma progression remain unclear. The elevated expression of thymidine kinase 1 (TK1) has been implicated in the progression of thyroid carcinoma, while the...

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Bibliographic Details
Main Authors: Chang Liu, Jian Wang, Li Zhao, Hui He, Pan Zhao, Zheng Peng, Feiyuan Liu, Juan Chen, Weiqing Wu, Guangsuo Wang, Fajin Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
thyroid carcinoma
thymidine kinase 1
thyroid nodules
progression
miR-34a-5p
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01475/full

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