P-94 METABOLIC SYNDROME IN PATIENTS WITH CHRONIC HEPATITIS C

Introduction: The interaction between hepatitis C and metabolic syndrome (MS) is widely discussed in the literature. Objective: To study the prevalence of MS in individuals with chronic hepatitis C and the associated clinical factors. Methodology: This is a cross-sectional study. The study included...

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Bibliographic Details
Main Authors: G.B.L. Menezes, C. Correia, M.I. Schinoni
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268121001551
Description
Summary:Introduction: The interaction between hepatitis C and metabolic syndrome (MS) is widely discussed in the literature. Objective: To study the prevalence of MS in individuals with chronic hepatitis C and the associated clinical factors. Methodology: This is a cross-sectional study. The study included 334 individuals with chronic hepatitis C, in which anthropometric variables, blood pressure and results of laboratory tests were analyzed. Result: The prevalence of MS in patients with hepatitis C was 2.4% (8/334). The mean values ​​of ALT were 90.1 ± 65.8; AST of 76.3 ± 70.4; and GGT of 130.2 ± 160, among those with HCV infection without MS. Among individuals with MS, ALT was 122.3 ± 82.3, AST was 76.7 ± 29.5, GGT was 102.3 ± 55.2. The steatosis found was 49.7% (166/334), while among individuals with MS, a frequency of 62.5% (5/8) was observed. F1 was 23.8% in HCV patients and, in SM, it was 12.5%; F2 48.5% and 37.5%, F3 22% and 37.5% and F4 5.7% and 12.5%. In individuals with hepatitis C and MS, systemic arterial hypertension was observed in 87.5% of cases, diabetes in 75%, dyslipidemia in 62.5% and obesity. Conclusion: MS had a low prevalence in HCV patients, and was associated, with a higher frequency of steatosis, greater inflammatory activity and more advanced liver fibrosis.
ISSN:1665-2681