Specific insulin and proinsulin in normal glucose tolerant first-degree relatives of NIDDM patients

Specific insulin and proinsulin in normal glucose tolerant first-degree relatives of NIDDM patients

In order to identify early abnormalities in non-insulin-dependent diabetes mellitus (NIDDM) we determined insulin (using an assay that does not cross-react with proinsulin) and proinsulin concentrations. The proinsulin/insulin ratio was used as an indicator of abnormal ß-cell function. The ratio of...

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Bibliographic Details
Main Authors: R. Coifman, I.S. Dalbosco, E.M.K. Russo, R.S. Moisés
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
insulin
NIDDM
proinsulin
first-degree relatives
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100010

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