The Hop Polyphenols Xanthohumol and 8-Prenyl-Naringenin Antagonize the Estrogenic Effects of Fusarium Mycotoxins in Human Endometrial Cancer Cells

The Hop Polyphenols Xanthohumol and 8-Prenyl-Naringenin Antagonize the Estrogenic Effects of Fusarium Mycotoxins in Human Endometrial Cancer Cells

The Fusarium toxin zearalenone (ZEN) and its reductive metabolite α-zearalenol (α-ZEL) are well-documented endocrine disruptors that are frequently found to contaminate cereal products, including beer. But also hop is known to represent a source for endocrine active compounds, containing amongst oth...

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Bibliographic Details
Main Authors: Georg Aichinger, Julia Beisl, Doris Marko
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Nutrition
Subjects:
flavonoid
xenoestrogen
mycoestrogen
interaction
combination index
synergism
Online Access:https://www.frontiersin.org/article/10.3389/fnut.2018.00085/full

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