Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis
<p>Abstract</p> <p>Background</p> <p>Leukotrienes are potent inflammatory mediators, which in a number of studies have been found to be associated with ischemic stroke pathology: gene variants affecting leukotriene synthesis, including the FLAP (ALOX5AP) gene, have in h...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-11-01
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Series: | BMC Neuroscience |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2202/13/146 |