Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis

<p>Abstract</p> <p>Background</p> <p>Leukotrienes are potent inflammatory mediators, which in a number of studies have been found to be associated with ischemic stroke pathology: gene variants affecting leukotriene synthesis, including the FLAP (ALOX5AP) gene, have in h...

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Bibliographic Details
Main Authors: Ström Jakob O, Strid Tobias, Hammarström Sven
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Neuroscience
Subjects:
Online Access:http://www.biomedcentral.com/1471-2202/13/146