Antihyperglycemic activity of Trichosanthes tricuspidata root extract

To evaluate the anti-diabetic activity of ethanolic extract of Trichosanthes tricuspidata root in alloxan induced diabetic rats and to perform the phytochemical screening. The extraction, preliminary phytochemical screening, anti-diabetic activity in alloxan induced diabetic rats  by oral administr...

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Bibliographic Details
Main Authors: Srinivasan Kulandaivel, Pawan Bajpai, Thangavel Sivakumar
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2013-07-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/15584
Description
Summary:To evaluate the anti-diabetic activity of ethanolic extract of Trichosanthes tricuspidata root in alloxan induced diabetic rats and to perform the phytochemical screening. The extraction, preliminary phytochemical screening, anti-diabetic activity in alloxan induced diabetic rats  by oral administration of  extract (200 and 400 mg/kg b.w.), the blood glucose level and biochemical parameters like cholesterol, triglyceride, serum protein, SGPT, SGOT, and ALP were estimated. Phytochemical studies shows the presence of carbohy-drates, proteins, glycosides and terpenoids and the ethanolic extract of T. tricuspidata root significantly lowered the blood sugar level. The above findings justified the traditional claim of anti-diabetic activity in this plant.
ISSN:1991-0088