Lapatinib and chronic renal insufficiency

Lapatinib is an intracellular tyrosine-kinase inhibitor of both EGFR (ErbB1) and HER2 (ErbB2) receptors, which is indicated in the treatment of metastatic disease pretreated with anti-HER2 therapies. We report the clinical case of a woman with chronic renal failure in dialysis affected by HER2-posi...

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Main Author: Luca Moscetti
Format: Article
Language:English
Published: AboutScience Srl 2018-03-01
Series:AboutOpen
Subjects:
Online Access:https://journals.aboutscience.eu/index.php/aboutopen/article/view/6
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spelling doaj-ccf6fcec401f4fe3bfca3f1820bd12cc2020-11-25T03:19:28ZengAboutScience SrlAboutOpen2465-26282018-03-014110.19156/abtpn.2018.0031Lapatinib and chronic renal insufficiencyLuca Moscetti0Dipartimento di Oncologia-Ematologia, Azienda Ospedaliero-Universitaria di Modena, Modena (Italy) Lapatinib is an intracellular tyrosine-kinase inhibitor of both EGFR (ErbB1) and HER2 (ErbB2) receptors, which is indicated in the treatment of metastatic disease pretreated with anti-HER2 therapies. We report the clinical case of a woman with chronic renal failure in dialysis affected by HER2-positive metastatic breast neoplasia and treated with lapatinib and letrozole (Oncology). https://journals.aboutscience.eu/index.php/aboutopen/article/view/6Lapatinibbreast cancermetastatic breast cancerHER2
collection DOAJ
language English
format Article
sources DOAJ
author Luca Moscetti
spellingShingle Luca Moscetti
Lapatinib and chronic renal insufficiency
AboutOpen
Lapatinib
breast cancer
metastatic breast cancer
HER2
author_facet Luca Moscetti
author_sort Luca Moscetti
title Lapatinib and chronic renal insufficiency
title_short Lapatinib and chronic renal insufficiency
title_full Lapatinib and chronic renal insufficiency
title_fullStr Lapatinib and chronic renal insufficiency
title_full_unstemmed Lapatinib and chronic renal insufficiency
title_sort lapatinib and chronic renal insufficiency
publisher AboutScience Srl
series AboutOpen
issn 2465-2628
publishDate 2018-03-01
description Lapatinib is an intracellular tyrosine-kinase inhibitor of both EGFR (ErbB1) and HER2 (ErbB2) receptors, which is indicated in the treatment of metastatic disease pretreated with anti-HER2 therapies. We report the clinical case of a woman with chronic renal failure in dialysis affected by HER2-positive metastatic breast neoplasia and treated with lapatinib and letrozole (Oncology).
topic Lapatinib
breast cancer
metastatic breast cancer
HER2
url https://journals.aboutscience.eu/index.php/aboutopen/article/view/6
work_keys_str_mv AT lucamoscetti lapatinibandchronicrenalinsufficiency
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