Preparation of Glycyrrhetinic Acid Liposomes Using Lyophilization Monophase Solution Method: Preformulation, Optimization, and In Vitro Evaluation

Preparation of Glycyrrhetinic Acid Liposomes Using Lyophilization Monophase Solution Method: Preformulation, Optimization, and In Vitro Evaluation

Abstract In this study, glycyrrhetinic acid (GA) liposomes were successfully prepared using lyophilization monophase solution method. Preformulation studies comprised evaluation of solubility of soybean phosphatidylcholine (SPC), cholesterol, and GA in tert-butyl alcohol (TBA)/water co-solvent. The...

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Bibliographic Details
Main Authors: Tingting Liu, Wenquan Zhu, Cuiyan Han, Xiaoyu Sui, Chang Liu, Xiaoxing Ma, Yan Dong
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:Nanoscale Research Letters
Subjects:
Glycyrrhizic acid
Liposomes
Monophase solution method
Preformulation
Cell uptake
Online Access:http://link.springer.com/article/10.1186/s11671-018-2737-5

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